The 38-year-old actress whoplays transexual Hayley Cropper was allowed a 12-month break due to exhaustion. Hesmondalgh said she wanted to spend more time with her husband Ian Kershaw and daughter Martha.
She will appear on screen again for the first time in September.
A source told The Mirror, "Julie just wanted to take time off and do normal things like take her daughter to school. Re-charging her batteries and being a mum was top of the agenda."
"Julie is such a popular member of the show that she really has been missed."