The 24-year-old actress has decided to leave Ramsay Street after five years of playing Carmella Cammeniti.
"I made the decision in December when I was doing a pantomime in the UK, but I cannot believe it is actually happening now," Natalie told the Herald Sun.
She added, "...Ideally, I would love to go to America. My heart is set on going to New York because I would love to keep training in musical theatre and developing my skills."